NAD+
For Research Use Only | Not for Human or Veterinary Use
Description:
NAD+ (Nicotinamide Adenine Dinucleotide, oxidized form) is a central coenzyme present in all living cells, functioning as a critical electron carrier in redox metabolism and as a co-substrate for NAD+-consuming enzymes including sirtuins (SIRT1–SIRT7), poly(ADP-ribose) polymerases (PARPs), and CD38/CD157 ectoenzymes. In preclinical laboratory research, NAD+ is extensively investigated for its role in cellular energy metabolism, DNA repair signaling, epigenetic regulation, and age-associated metabolic decline. As a dinucleotide composed of adenine and nicotinamide mononucleotide linked by pyrophosphate, NAD+ serves as a fundamental research tool in bioenergetics, aging biology, and metabolic pathway analysis.
Scientific Specifications:
- Compound Name: NAD+ (Nicotinamide Adenine Dinucleotide)
- Type: Dinucleotide Coenzyme
- Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
- Molecular Weight: 663.43 g/mol
- CAS Number: 53-84-9
- PubChem CID: 5892
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
NAD+ is commonly studied for its potential effects on:
- Sirtuin (SIRT1–SIRT7) activation and NAD+-dependent deacetylase/deacylase activity
- Mitochondrial oxidative phosphorylation and electron transport chain function
- PARP-mediated DNA damage repair and genomic stability maintenance
- Age-related NAD+ decline and its impact on cellular metabolic fitness
- CD38 ectoenzyme activity and NAD+ consumption in inflammatory signaling models
- NAD+/NADH redox ratio dynamics and metabolic flux analysis
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
