KISSPEPTIN-10
For Research Use Only | Not for Human or Veterinary Use
Description:
Kisspeptin-10 is a synthetic decapeptide fragment derived from the KISS1 gene product, playing a pivotal role in initiating the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. It acts as a potent agonist of the GPR54 (KISS1R) receptor and is a key regulator of the hypothalamic-pituitary-gonadal (HPG) axis. Kisspeptin-10 represents the shortest bioactive fragment of the full-length kisspeptin-54 protein, retaining high receptor binding affinity and biological activity in reproductive neuroendocrine research.
Scientific Specifications:
- Peptide Name: Kisspeptin-10 (Metastin 45-54)
- Type: Synthetic Decapeptide (10 amino acids)
- Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
- Molecular Formula: C₆₃H₈₃N₁₇O₁₄
- Molecular Weight: 1302.45 g/mol
- CAS Number: 374675-21-5
- PubChem CID: 25240297
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
Kisspeptin-10 is commonly studied for its potential effects on:
- GnRH release stimulation and reproductive axis activation
- GPR54/KISS1R receptor agonism and downstream signaling
- Hypothalamic-pituitary-gonadal (HPG) axis regulation
- Fertility and puberty onset research models
- Anti-metastatic signaling in tumor biology models
- Neuroendocrine regulation of gonadotropin (LH/FSH) secretion
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
