SERMORELIN

For Research Use Only | Not for Human or Veterinary Use

Description:
Sermorelin (GRF 1–29 NH₂) is a synthetic 29-amino acid peptide corresponding to the first 29 residues of endogenous growth hormone-releasing hormone (GHRH). In preclinical laboratory research, Sermorelin is extensively investigated as a GHRH receptor (GHRH-R) agonist that stimulates somatotroph cells of the anterior pituitary to release growth hormone (GH) through a cAMP-dependent signaling pathway. The peptide retains full biological activity of the native 44-amino acid GHRH, as residues 1–29 constitute the minimal bioactive sequence required for receptor binding and activation. Sermorelin serves as a fundamental research tool in neuroendocrinology, GH axis physiology, and pulsatile hormone secretion studies.

Scientific Specifications:

• Peptide Name: Sermorelin (GRF 1–29 NH₂)
• Type: Synthetic 29-Amino Acid Peptide (GHRH Analogue)
• Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
• Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
• Molecular Weight: 3357.9 g/mol
• CAS Number: 86168-78-7
• PubChem CID: 16132413
• Form: Lyophilized powder
• Storage: Store dry in a cool, dark environment (2°C to 8°C)

Research Context:
Sermorelin is commonly studied for its potential effects on:

• GHRH receptor binding kinetics and cAMP-dependent somatotroph cell activation
• Pulsatile growth hormone secretion patterns and GH axis feedback regulation
• IGF-1 axis downstream signaling and hepatic somatomedin production pathways
• Age-related somatopause and declining GH secretory capacity in aging research models
• Anterior pituitary function assessment and neuroendocrine reserve testing paradigms
• Comparative GHRH receptor pharmacology with modified and truncated GHRH analogues

Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.

Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.

Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.